The exploration staff explained the receptor as an “opioid scavenger” thanks to its power to entice naturally transpiring opioids ahead of they can connect with classical opioid receptors.
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These final results, together with a former report displaying that a small-molecule ACKR3 agonist CCX771 reveals anxiolytic-like behavior in mice,two help the strategy of focusing on ACKR3 as a unique strategy to modulate the opioid method, which could open new therapeutic avenues for opioid-lin
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We shown that, in contrast to classical opioid receptor
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